DIAZOXIDE - ORAL (Proglycem) side effects, medical uses.
Diazoxide raises blood sugar by slowing the release of insulin from the pancreas. Diazoxide is used to treat low blood sugar (hypoglycemia) caused by certain cancers or other conditions that can make the pancreas release too much insulin.This medicine is for use in adults and children as young as infants. Diazoxide may also be used for purposes not listed in this medication guide.
Diazoxide is given by rapid intravenous injection for the urgent reduction of high blood pressure in patients with all grades of renal function. Oral diazoxide produces less consistent effects. Protein binding of diazoxide is reduced in renal failure and this can be related to reduction of albumin concentration.
Diazoxide vs labetalol: a cross-over comparison of short-term effects in hypertension.. It is concluded that the acute effects of intravenous labetalol are comparable to those of diazoxide and that labetalol can be used with advantage as a complemental alternative to diazoxide in the emergency treatment of some hypertensive crises.
Standard preparation— Dissolve an accurately weighed quantity of USP Diazoxide RS in methanol,and dilute quantitatively,and stepwise if necessary,with methanol to obtain a solution having a known concentration of about 1mg per mL.Transfer 5.0mLof this solution to a 100-mLvolumetric flask,add 2.0mLof Internal standard solution, dilute with a mixture of water and methanol (4:1)to volume,and.
Find patient medical information for Diazoxide Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
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A variety of pharmacological agents A variety of pharmacological agents affect glucose homeostasis resulting in either hypo- or hyperglycemia. Hormones such as insulin, glucagon, catecholamines, growth hormone, and cortisol, among others, contribute to normoglycemia. Drug-induced serum glucose alterations manifested as hyperglycemia or hypoglycemia can have perpetual effects on the body.